Soyuz.

About five percent of the people that have been launched have died doing so (because astronauts often launch more than once). As of November 2004, 439 individuals have flown on spaceflights: Russia/Soviet Union (96), USA (277), others (66). Twenty-two have died while in a spacecraft: three on Apollo 1, one on Soyuz 1, one on X-15-3, three on Soyuz 11, seven on Challenger, and seven on Columbia. By space program, 18 NASA astronauts (4.1%) and four Russian cosmonauts (0.9% of all the people launched) died while in a spacecraft.